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PUBLICATIONS

Highlighted Publications
List of Publications in Peer-Reviewed Journals

28. TBA

S. Varlas,†* E. C. Johnson,† O. Norvilaite, T. J. Neal, G. J. Leggett, S. P. Armes

Manuscript in preparation.

27. Thermoresponsive Block Copolymer Core–Shell Nanoparticles with Tunable Flow Behavior in Porous Media

M. P. J. Miclotte, S. Varlas, C. D. Reynolds, B. Rashid, E. Chapman, R. K. O'Reilly

ACS Appl. Mater. Interfaces 2022, 14, 54182-54193.

Open-access article

26. Synthesis of crystallizable poly(behenyl methacrylate)-based block and statistical copolymers and their performance as wax crystal modifiers

I. R. Dorsman, D. H. H. Chan, V. J. Cunningham, S. L. Brown, C. N. Williams, S. Varlas,* S. P. Armes

Polym. Chem. 2022, 13, 5861-5872.

Open-access article

25. Stimuli-responsive and core cross-linked micelles developed by NiCCo-PISA of helical poly(aryl isocyanide)s

S. Jimaja, S. Varlas, J. C. Foster, D. Taton, A. P. Dove, R. K. O'Reilly

Polym. Chem. 2022, 13, 4047-4053.

Open-access article

24. Polymerization-induced self-assembly and disassembly during the synthesis of thermoresponsive ABC triblock copolymer nano-objects in aqueous solution

S. Varlas,* T. J. Neal, S. P. Armes

Chem. Sci. 2022, 13, 7295-7303.

Open-access article

23. Protein-, (Poly)peptide-, and Amino Acid-Based Nanostructures Prepared via Polymerization-Induced Self-Assembly

S. Varlas,* G. L. Maitland, M. J. Derry 

Polymers 2021, 13, 2603.

Open-access article

22. Tuning the Cloud-Point and Flocculation Temperature of Poly(2-(diethylamino)ethyl methacrylate)-Based Nanoparticles via a Postpolymerization Betainization Approach

M. P. J. Miclotte, S. B. Lawrenson, S. Varlas, B. Rashid, E. Chapman, R. K. O'Reilly

ACS Polym. Au 2021, 1, 47-58.

Featured in Top 10 Most Accessed Articles during July-October 2021 and in Top 10 Most Accessed list in 2021 – Open-access article

21. Complementary Nucleobase Interactions Drive the Hierarchical Self-Assembly of Core–Shell Bottlebrush Block Copolymers toward Cylindrical Supramolecules

S. Varlas,† Z. Hua,† J. R. Jones, M. Thomas, J. C. Foster, R. K. O'Reilly

Macromolecules 2020, 53, 9747-9757.

20. It is Better with Salt: Aqueous Ring-Opening Metathesis Polymerization at Neutral pH

J. C. Foster,† M. C. Grocott,† L. A. Arkinstall, S. Varlas, M. J. Redding, S. M. Grayson, R. K. O'Reilly

J. Am. Chem. Soc. 2020, 142, 13878-13885.

Open-access article

19. Self-assembled nanostructures from amphiphilic block copolymers prepared via ring-opening metathesis polymerization (ROMP)

S. Varlas, S. B. Lawrenson, L. A. Arkinstall, R. K. O'Reilly, J. C. Foster

Prog. Polym. Sci. 2020, 107, 101278.

18. The Importance of Cooperativity in Polymer Blending: Toward Controlling the Thermoresponsive Behavior of Blended Block Copolymer Micelles

R. Keogh, L. D. Blackman, J. C. Foster, S. Varlas, R. K. O'Reilly

Macromol. Rapid Commun. 2020, 41, 1900599.

Part of Special Issue on "Women in Polymer Science"

17. Nickel-Catalyzed Coordination Polymerization-Induced Self-Assembly of Helical Poly(Arylisocyanide)s

S. Jimaja, S. Varlas, Y. Xie, J. C. Foster, D. Taton, A. P. Dove, R. K. O'Reilly

ACS Macro Lett. 2020, 9, 226-232.

Featured in Top 20 Most Accessed Articles list in February 2020

16. Polymerization-Induced Polymersome Fusion

S. Varlas, R. Keogh, Y. Xie, S. L. Horswell, J. C. Foster, R. K. O'Reilly

J. Am. Chem. Soc. 2019, 141, 20234-20248.

Open-access article

15. Macromolecular Architecture and Encapsulation of the Anticancer Drug Everolimus Control the Self-Assembly of Amphiphilic Polypeptide-Containing Hybrids

A. Karatzas,† J. S. Haataja,† D. Skoulas, P. Bilalis, S. Varlas, P. Apostolidi, S. Sofianopoulou, E. Stratikos, N. Houbenov, O. Ikkala, H. Iatrou

Biomacromolecules 2019, 20, 4546-4562.

14. Ring-opening metathesis polymerization-induced self-assembly (ROMPISA)

S. Varlas, J. C. Foster, R. K. O'Reilly

Chem. Commun. 2019, 55, 9066-9071.

Part of Themed Collection: " 2020 RSC Prize and Award winners" – Open-access article

13. Tuning the membrane permeability of polymersome nanoreactors developed by aqueous emulsion polymerization-induced self-assembly

S. Varlas, J. C. Foster, P. G. Georgiou, R. Keogh, J. T. Husband, D. S. Williams, R. K. O'Reilly

Nanoscale 2019, 11, 12643-12654.

Open-access article

12. Predicting Monomers for Use in Aqueous Ring-Opening Metathesis Polymerization-Induced Self-Assembly

S. Varlas, J. C. Foster, L. A. Arkinstall, J. R. Jones, R. Keogh, R. T. Mathers, R. K. O'Reilly

ACS Macro Lett. 2019, 8, 466-472.

Featured as Top 1 Most Accessed Article in May and June 2019 and in Top 10 Most Accessed list in 2019 – Open-access article

11. Getting into Shape: Reflections on a New Generation of Cylindrical Nanostructures’ Self-Assembly using Polymer Building Blocks

J. C. Foster, S. Varlas, B. Couturaud, Z. Coe, R. K. O'Reilly

J. Am. Chem. Soc. 2019, 141, 2742-2753.

Highlighted as Highly Cited Paper in Web of Science – Open-access article

10. Poly(Pentafluorophenyl Methacrylate)‐Based Nano‐Objects Developed by Photo‐PISA as Scaffolds for Post‐Polymerization Functionalization

B. Couturaud,† P. G. Georgiou,† S. Varlas, J. R. Jones, M. C. Arno, J. C. Foster, R. K. O'Reilly

Macromol. Rapid Commun. 2019, 40, 1800460.

Part of Special Issue on "Polymerization-Induced Self-Assembly"

9. Poly(Sarcosine)-Based Nano-Objects with Multi-Protease Resistance by Aqueous Photoinitiated Polymerization-Induced Self-Assembly (Photo-PISA)

S. Varlas, P. G. Georgiou, P. Bilalis, J. R. Jones, N. Hadjichristidis, R. K. O'Reilly

Biomacromolecules 2018, 19, 4453-4462.

8. Predicting Monomers for use in Polymerization-Induced Self-Assembly

J. C. Foster, S. Varlas,† B. Couturaud,† J. R. Jones, R. Keogh, R. T. Mathers, R. K. O'Reilly

Angew. Chem. Int. Ed. 2018, 57, 15733-15737.

Highlighted as Very Important Paper by the editorial board

7. Photoinitiated Polymerization-Induced Self-Assembly in the Presence of Surfactants Enables Membrane Protein Incorporation into Vesicles

S. Varlas, L. D. Blackman, H. E. Findlay, E. Reading, P. J. Booth, M. I. Gibson, R. K. O'Reilly

Macromolecules 2018, 51, 6190-6201.

Open-access article

6. Ring‐Opening Metathesis Polymerization in Aqueous Media using a Macroinitiator Approach

J. C. Foster, S. Varlas, L. D. Blackman, L. A. Arkinstall, R. K. O'Reilly

Angew. Chem. Int. Ed. 2018, 57, 10672-10676.

5. Confinement of Therapeutic Enzymes in Selectively Permeable Polymer Vesicles by Polymerization-Induced Self-Assembly (PISA) Reduces Antibody Binding and Proteolytic Susceptibility

S. Varlas,† L. D. Blackman,† M. C. Arno, Z. H. Houston, N. L. Fletcher, K. J. Thurecht, M. Hasan, M. I. Gibson, R. K. O'Reilly

ACS Cent. Sci. 2018, 4, 718-723.

Featured in Top 10 Most Accessed list in May and June 2018 – Open-access article

4. Smart polymersomes and hydrogels from polypeptide-based polymer systems through α-amino acid N-carboxyanhydride ring-opening polymerization. From chemistry to biomedical applications

E. Liarou, S. Varlas, D. Skoulas, C. Tsimblouli, E. Sereti, K. Dimas, H. Iatrou

Prog. Polym. Sci. 2018, 83, 28-78.

3. Permeable Protein-Loaded Polymersome Cascade Nanoreactors by Polymerization-Induced Self-Assembly

L. D. Blackman, S. Varlas, M. C. Arno, A. Fayter, M. I. Gibson, R. K. O'Reilly

ACS Macro Lett. 2017, 6, 1263-1267.

Featured in Most Accessed list in November and December 2017 – Open-access article

2. pH-Sensitive nanogates based on poly(L-histidine) for controlled drug release from mesoporous silica nanoparticles

P. Bilalis, L.-A. Tziveleka, S. Varlas, H. Iatrou

Polym. Chem. 2016, 7, 1475-1485.

Selected as Paper of the Month in Polymer Chemistry in February 2016

1. Preparation of hybrid triple‐stimuli responsive nanogels based on poly(L‐histidine)

P. Bilalis, S. Varlas, A. Kiafa, A. Velentzas, D. Stravopodis, H. Iatrou

J. Polym. Sci. Part A: Polym. Chem. 2016, 54, 1278-1288.

† Denotes equal author contribution

* Denotes corresponding authorship

Conference Proceedings

Thus far, I have delivered 16 oral presentations (including 8 invited talks and 1 "Best Oral Presentation" prize) and 14 poster presentations (including 2 "Best Poster" prizes) in national, international and online conferences and meetings.

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6. Tuning membrane properties of functional polymersomes developed via aqueous photoinitiated polymerization-induced self-assembly (photo-PISA)

S. Varlas, L. D. Blackman, J. C. Foster, M. C. Arno, M. I. Gibson, R. K. O'Reilly

Abstr. Pap. Am. Chem. Soc. 2020, 259, PMSE-0696.

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5. Expanding the scope of aqueous ring-opening metathesis polymerization-induced self-assembly (ROMPISA)

S. Varlas, J. C. Foster, R. Keogh, L. A. Arkinstall, R. T. Mathers, R. K. O'Reilly

Abstr. Pap. Am. Chem. Soc. 2020, 259, PMSE-0695.

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4. Evolution of tubesomes via polymerization-induced polymersome fusion

S. Varlas, R. Keogh, Y. Xie, R. Keogh, J. C. Foster, R. K. O'Reilly

Abstr. Pap. Am. Chem. Soc. 2020, 259, POLY-0647.

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3. Tuning the membrane permeability of polymersome nanoreactors developed by aqueous emulsion polymerization-induced self-assembly

S. Varlas, J. C. Foster, P. G. Georgiou, R. Keogh, J. T. Husband, D. S. Williams, R. K. O'Reilly

Abstr. Pap. Am. Chem. Soc. 2020, 259, POLY-0257.

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2. Nanostructure synthesis by ring-opening metathesis polymerization-induced self-assembly

J. C. Foster, S. Varlas, L. A. Arkinstall, R. Keogh, R. K. O'Reilly

Abstr. Pap. Am. Chem. Soc. 2019, 258, 84-POLY.

1. Advances in aqueous metathesis chemistry

J. C. Foster, S. Varlas, L. A. Arkinstall, R. K. O'Reilly

Abstr. Pap. Am. Chem. Soc. 2019, 258, 63-PMSE.

Theses

Tuning the membrane properties of functional polymersomes developed by aqueous polymerization-induced self-assembly (PISA) – Download

S. Varlas – Ph.D. Thesis

University of Birmingham, 2020.

Synthesis, characterization and self-assembly of stimuli-responsive copolymers of poly(ethylene oxide), poly(L-histidine) and poly(L-cysteine) for the encapsulation of anticancer drugs and their controlled release – Download

S. Varlas – M.Sc. Thesis (in Greek)

National and Kapodistrian University of Athens, 2016.

Encapsulation of anticancer drugs into polypeptide-based nanostructures – Download

S. Varlas – B.Sc. Thesis (in Greek)

National and Kapodistrian University of Athens, 2014.

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